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Top Ten Benefits of Microscope-based Telepathology

Since the 1980s, telepathology has been providing an efficient and effective means to review patient samples by a remote pathologist.  Although considered to be an antiquated technique by some, microscope-based telepathology still affords healthcare institutions and pathologists a list of benefits (and features) that are still unmatched by many whole slide imaging technologies.

With a microscope-based telepathology system, you can…

  1. Review glass slides on-site or remotely.
  2. Invite one or more specialists for live, simultaneous remote viewing and consultation.
  3. Use the full optical resolution of multiple objectives.
  4. Freely adjust focus on the fly through thick and thin samples.
  5. Review slides immediately without interrupting a scan or adding slides to a queue for scanning.
  6. Review wet mounts, frozen sections, FNAs.
  7. Use other contrast methods than histological staining (i.e., polarization, darkfield).
  8. Use 1” x 3” and 2” x 3” slides.
  9. Use oil immersion.
  10. Use the microscope as a conventional stand-alone microscope.

Are you interested in learning more about the RC500 Remote Collaboration System for Live Telepathology?

CLICK HERE to request a demonstration

Click Here to Download the RC500 Brochure

Click Here to  view more details about RC500

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Doing More with Less Through Telepathology

From recent surveys, studies and medical school records, the pathology gap (imbalance between practitioners vs growing incidence of disease) is further exacerbated by impending retirements, a decline in graduation rates, and entry into subspecialties (when adjusted for population levels). [1]

Further complicating this pathology gap are continued cost-cutting measures imposed by independent institutions, facilities, insurers, and agencies such as the Centers for Medicare and Medicaid Services.  In their latest ruling on the physician fee schedule, the CMS reported that there will be a 1.25% overall reduction in the CY 2024 PFS from CY 2023. [2]  By comparison, there was no overall reduction from CY 2022 to CY 2023.  Tightening the belt even further, the 3.75% temporary CY 2021 payment increase provided by the Consolidated Appropriations Act, 2021 is set to expire.

How can pathologists and healthcare institutions do more with less?

Streamline the pathology workflow: 

Following the concept of lean production, pathologists can focus on the work that they do best by off-loading other work to pathology assistants (e.g., tissue grossing) and other care extenders. [1]  This leaves the pathologist to focus their resources on what only they can do – confirm findings and sign the case report.

Extend access to pathologists:

Telepathology enables access to pathologists and sub-specialists, regardless of location.  Even when the pathologist is in the same facility, they can readily review live patient cases via remote viewing to render or confirm findings and, without further delay, advance care for the patient.  When the pathologist is not located in the facility with the patient slides, they can still utilize remote telepathology to view the patient samples.  Used in conjunction with ROSE cases, remote telepathology can translate into shortened OR time for the patient, thus reducing overall costs for the patient, insurer, and healthcare system.  Following suit, specialists can also be utilized via telepathology to review challenging cases.

How can the ACCU-SCOPE® RC500 Remote Telepathology System help close the pathology gap and ease the burden on the healthcare system?

The RC500 Remote Collaboration System was developed to address the need for live telepathology and as an alternative to costly slide scanning methods.  Through remote sharing technology, a pathologist can review glass slides from any location and at any time.

Through telepathology, the RC500 enables the remote reviewing of patient slides regardless of proximity to the laboratory.  Likewise, the patient care team also benefits from live telepathology by enabling access to readily available sub-specialists when additional expertise is required.  Additionally, live telepathology, as in FNAs and ROSE, improves patient care by shortening the time for review and accelerating treatment.

Would you like to learn more about the RC500 Remote Collaboration System for Live Telepathology?

CLICK HERE to request a demonstration

Click Here to  view more details about RC500

Click Here to Download the RC500 Brochure

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Can “Live” Telepathology Improve Pathologist QOL?

It is well known that a physician’s wellbeing and Quality of Life can impact the quality of treatment. [1]  Without specialization, pathologists split their time between anatomical pathology, clinical lab work, teaching, research and administrative duties. [2]  Sub-specialization in pathology creates opportunity for improved learning, leading to higher satisfaction with diagnoses in those specialties.  More specialized work has also shown improvement in the quality of diagnosis. [3]

Other stresses plague pathologists.  Case load and pathologist accessibility are high on this list.  So how can live, real-time telepathology further improve the pathologist’s QOL and the quality of patient care?

  • Convenient live slide evaluation from any location, within or outside the institution.
  • Live consultation for accelerated diagnoses, faster treatment and better patient outcomes.
  • Increased efficiency in case review, reduced waiting time, and opportunity to review more cases.
  • More opportunities for training (and mentoring) by sharing sessions with fellow pathologists and specialists.
  • Improved access to specialist consultations, even when not on-site.
  • Reduced cost and risk of breakage from transportation of slides to the pathologist for evaluation.
  • Expanded convenience and flexibility affording pathologists enhanced work-life balance.
  • Enhanced ability to collaborate and share knowledge between institutions.

Are you using live remote telepathology, or is it in your future?  The ACCU-SCOPE RC500 Remote Collaboration System can support your telepathology goals and enhance your quality of care.

Interested in a demonstration of the RC500? CLICK HERE to request a demonstration

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Advantages of Live, Real-Time Telepathology

Microscope technology has evolved tremendously over the past several decades, far beyond simply adjusting light intensity, changing objectives, and positioning and focusing a specimen — with digital telepathology, anyone with an internet connection can review microscopic samples remotely. Let’s examine what real-time telepathology is and the advantages that microscopes like the ACCU-SCOPE RC500 have over traditional models.

What Is Digital Pathology?

Digital pathology first emerged in the 1980s and has advanced considerably since its introduction. Thanks to numerous technological advancements over the years, it is now an indispensable part of countless institutions.

In its infancy, digital pathology relied on the capture and sharing of static images with the remote reviewer. Digital pathology has evolved to utilize whole-slide imaging to scan and digitize entire glass slides, then store and share the digital slide files via the internet. In addition to capturing static specimen images, some digital pathology technology can capture and permit the viewing (streaming) of live images as well.

The creation of high-quality specimen imagery allows individuals to easily view, analyze, and manage pathology samples on an electronic device of their choice. In short, digital telepathology allows for remote functionality over long distances so long as there is an established internet connection.

The Benefits of Real-Time Telepathology

One of the greatest strengths of real-time telepathology is that it allows a remote user to access and review live images of patient slides from long (or not-so-long) distances. This is particularly useful given the increasingly constrained availability of pathologists, including when they are not local to the hospital labs for in-person viewing.

For example, real-time telepathology enables healthcare professionals to review slides from patient cases in rural regions without having to transfer the physical slides to a faraway hospital. Given how delays in diagnosis can be dangerous, real-time telepathology has the potential to save lives through its accessibility to pathologists, regardless of their location. Remote functionality also allows remote viewers to review samples from biopsies and fine needle aspirates (FNA) while the patient is still in the operating room.

In addition, this innovative approach to pathology can help reduce costs and improve the speed and quality of patient care. It allows sub-specialists to review difficult cases or provide second opinions and enhances the coordination and communication between all medical personnel in a particular patient’s care team. The accelerated decision-making brought about by this remote collaboration leads to greater productivity, improving patient care as a result.

The ACCU-SCOPE RC500 is a remote collaboration system designed for real-time telepathology and consists of a motorized microscope, motorized stage, computer, and software. By logging into the RC500 computer desktop, a remote viewer has full control of the microscope and specimen position – the only operation the remote reviewer cannot do is place the slide on the stage. It’s worth noting that the RC500 can also function as a traditional microscope when not being used for telepathology, allowing for greater flexibility and multipurpose usage in the laboratory.

What Is Rapid On-Site Evaluation?

Rapid On-Site Evaluation (ROSE) refers to the near-immediate review of a patient sample by a pathologist. Tissue biopsies are taken from a patient in the operating room (OR), the biopsies are prepared and reviewed by a pathologist, all while the patient is still in the OR. Normally, this would involve the pathologist visiting the pathology (frozen section) laboratory located near the OR. Thanks to real-time telepathology, the pathologist doesn’t need to come down to the frozen section lab to review the sample — rather, they can do so quickly and conveniently from their office.

OSEA (On-Site Evaluation of Adequacy) is one version of ROSE in which fine needle aspiration (FNA) types of biopsies are reviewed to provide a quick determination of whether there is sufficient (adequate) cellular content for a cytopathologist or pathologist to render a diagnosis, classification or disease stage of the specimen. As pathologists are not always readily available to review a ROSE case, a cytopathologist or cytotechnologist may also not be available to review OSEA cases and, therefore, remote telepathology can play a critical part in providing fast access to the medical experts to determine sample adequacy.

Applications of Remote Telepathology

There are numerous medical disciplines that utilize remote telepathology, including pathology, cytopathology, hematopathology, anatomic pathology, microbiology, dermatopathology, and many more. As such, the seamless automation and remote viewership of this technology naturally lead to a diverse range of applications.

For example, remote telepathology can be utilized in healthcare settings for patient diagnosis, clinical research, and even resident training. In addition, this technology is a highly effective tool in educational environments beyond just healthcare. Digital images can be acquired from any specimen, saved to a network or the cloud, and then accessed from any device, allowing students to easily view the digitized samples outside of class. Furthermore, the digitized samples ensure that all students experience the same “slides” and the same locations/features on the slides, thereby standardizing the learning experience.

If You’re Interested in Learning More About an RC500 Microscope for Your Institution, Contact ACCU-SCOPE Today

To bring the benefits of remote functionality to your laboratory, reach out to ACCU-SCOPE. In addition to the RC500 microscope, we also supply traditional microscopes, high-quality digital imaging cameras, and more. Contact us today for further information and to place an order for your organization.

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ACCU-SCOPE Introduces Remote Collaboration Microscopy System for Pathology and Research

Commack, NY [June 2023] – ACCU-SCOPE Inc. is pleased to announce the development and launch of the RC500 Remote Collaboration Microscopy System.  The RC500 is fully integrated with motorized microscope, high-resolution, medical device-grade camera, and software.  The RC500 is designed for stand-alone operation for local, in-person microscopy, as well as full operation by a remote user via a desktop sharing application.  The RC500 provides the best of three worlds: traditional microscopy using eyepieces, improved ergonomics using the included camera and display on the monitor, and remote viewing of images by researchers and collaborators.

“Despite the movement of clinical microscopy towards whole slide imaging, there is still and absolutely a place for traditional microscopes in the clinic, laboratory, tumor boards, seminar and instructional environments,” says Brian Taub, CEO of ACCU-SCOPE.  “This has been a resounding message from pathologists, veterinary pathologists, and researchers over the past couple of years.  Slide scanners are indeed great, but they haven’t replaced the traditional microscope.”  The RC500 is a highly versatile system addressing the needs for peer-to-peer collaboration, remote consultation, and routine microscopy, and slide scanners don’t offer all three.  The RC500 delivers exceptional images plus the added benefit of excellent agility in today’s busy world of pathology and research.

Figure 1. RC500 user interface.

Figure 2. RC500 system can be operated remotely from any PC, tablet or smartphone with internet connection and desktop sharing app.
Figure 3. The RC500 offers real-time remote viewing, control and collaboration. Remote viewers and users can position the slides, change objective magnifications and annotate for a true interactive experience.

The RC500 is a fully functional clinical and research-grade upright microscope featuring a trinocular viewing head; 4x, 10x, 20x, 40x and 60x dry semi-Apochromatically corrected objectives (no need for oil immersion); motorized stage with XY stage stalks and 2-slide holder; front touchscreen LCD display on the microscope; high-speed medical device-grade color microscopy camera; and preconfigured RC500 software.  RC500 provides both the local and remote user with fingertip access to objective selection, “manual” and auto focusing, XY specimen positioning, digital zoom, image adjustment, overview scan, pin drops, heat map, annotations, and more.

Contact ACCU-SCOPE for more information about the microscope or to schedule a remote demonstration of the RC500 Remote Collaboration System.

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About ACCU-SCOPE Inc.

As a market leader in quality microscopy and imaging solutions, ACCU-SCOPE blends precision, performance and outstanding value like no other manufacturer can. We deliver superb yet affordable optical instrumentation and microscopy innovations that help advance the work, improve the outcomes and empower the achievements of the demanding professionals we’re privileged to serve. For more information about ACCU-SCOPE, please contact info@www.accu-scope.com.

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NEW Plan APO Objectives from ACCU-SCOPE

Commack, NY, USA [April 2023] – ACCU-SCOPE is pleased to introduce a line of Apochromatically-corrected (“APO”) objectives for upright (compound) and inverted microscopes.  The APO objectives complement the existing line of high-quality Plan Achromat and Plan Semi-Apochromatic objectives.

The new APO objectives were designed for the EXC-500 microscope – ACCU-SCOPE’s flagship clinical and biological upright microscope – the new APO lenses are also suitable for use on ACCU-SCOPE’s EXI-410 and EXI-600 inverted microscopes, provided the sample slides use a standard No. 1½ coverglass (0.17mm thickness).  Featuring higher Numerical Apertures and improved color correction than the Semi-Apochromatic or Achromat objectives, APO objectives deliver brighter images, shallower depth of field and higher resolution for improved observation of fine details.  APO objectives are ideal for brightfield observation, imaging and fluorescence applications, or where the highest color fidelity is desired.  The M25 thread size and 200mm tube length also allow these objectives to be used on most Nikon upright microscopes.

For more information, contact us at info@www.accu-scope.com.

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Contact Us to learn more

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A Look at Stereo Microscopes and Their Applications

There is a wide array of microscopes available for scientists to use, each with their own functions, features, capabilities and applications. The stereo microscopes offer users a variety of unique benefits that aren’t provided by other microscopes. Here is an overview of this unique style of microscope, what makes it different, and why it has found application throughout countless industries.

What Is a Stereo Microscope?

Stereo microscopes, also referred to as dissecting microscopes, examine 3-dimensional (3D) specimens, as opposed to conventional microscopes, which observe what are essentially 2-dimensional (flat) samples on slides. The objective lenses and eyepieces of stereo microscopes are independent, creating two distinct optical paths for the user’s eyes.  The optical paths begin at the eyes and converge at the focal position on the sample, thereby generating the 3D view (see the figure below). Zoom stereo microscopes allow adjustable magnification for more precise viewing, whereas some stereo microscopes may only have fixed magnifications. Auxiliary lenses are often available and allow the user to adjust the magnification to better fit their needs and/or the working distance (distance between the bottom of the microscope and the focal position on the sample).

Resulting from the optical design, stereo microscopes are fundamentally different from compound microscopes. The stand of a stereo microscope is almost as important as the microscope itself.  The stand can make a difference in how the sample is illuminated: from the top, bottom, on angle, or combinations of these, and the stand and illumination method are often selected based on the sample and the best way to observe it. Transmitted-style stands shine light from underneath and through the sample, which works best with transparent specimens. Incident lighting stands illuminate the sample from above or from the side using a light that is attached to the stand, a ring light, or other techniques. By controlling the angle of the incident light, small details can be revealed and more easily observed by the operator.

Additionally, stereo microscopes generally operate at lower magnifications than other types of microscopes and therefore generally, due to the physics of light and optics, have larger working distances (distance between the bottom of the microscope body and the top of the sample). In combination with the 3D viewing, the large working distances allow the operators more room for manipulation (e.g., dissection), the use of tools and the ability to reposition.  As a result, stereo microscopes.

Two Types of Stereo Microscopes?

That’s right, there are two distinct optical designs for stereo microscopes.  Stereo microscopes with a Greenough optical design have two completely independent optical paths.  The Greenough-design is what is typically associated with dissecting microscopes. Common Main Objective (CMO), Parallel or Galilean optical design stereo microscopes are distinguished by a large objective on the bottom of the microscope’s optical body.  CMO stereo microscopes generally provide higher magnification and higher resolution than their Greenough cousins.  As a result, CMO microscopes are more frequently used for imaging and documentation than dissection and sample manipulation – the exception is when observing specimens such as embryos, organoids and spheroids.

What Is a Stereo Microscope Used For?

The stereo microscope is superior to compound microscopes in viewing three-dimensional samples and their surface characteristics, making it the tool of choice for tasks requiring direct interaction with the material. As a result, they have many applications across a wide range of industries.  In academic settings, stereo microscopes are frequently used for dissections of both plant and animal samples, observation of model organisms (e.g., fruit flies, worms and fish) and other uses thanks to the zoom ranges, excellent depth perception and ease of specimen handling. Stereo microscopes are generally more portable than other microscopes, providing greater convenience and suitability for field work. Furthermore, the 3D viewing offered by stereo microscopes has led to their usage beyond biology dissections — botany, geology, gemology, and industrial applications capitalize on the unique capabilities of stereo microscopes for the observation of surface details and sample manipulation.

For High-Quality Stereo Microscopes and Other Products, Contact ACCU-SCOPE Today

If you would like to acquire high-quality stereo microscopes for your laboratory, reach out to ACCU-SCOPE. We offer various stereo microscope systems, microscope accessories, and a wide range of other products. To learn more about what a stereo microscope is best for your application, contact ACCU-SCOPE for additional information.

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See ACCU-SCOPE Microscopes at VMX 2023

ACCU-SCOPE Inc. is pleased to announce that several of its clinical microscopes are on display at VMX 2023 in Orlando, FL this week.  ACCU-SCOPE clinical microscopes are proven to deliver robust and dependable performance at a reasonable price.

The EXC-500 motorized microscope (EXC-500-MOT) is ACCU-SCOPE’s newest microscope and features motorized focus, a motorized nosepiece, an LCD touchscreen display and finger-tip hot buttons for fast changing of objectives and illumination intensity.  The EXC-500-MOT is key component in the Cellfie® Telemedicine Enabled Pathology System from Companion Animal Health (a division of LiteCure, LLC and DJO Global).  Cellfie® utilizes remote-enabled technologies to provide true point-of care pathology solutions for veterinary health.  See the Cellfie system in operation at the Companion Animal Health booth.

The ACCU-SCOPE 3000-LED and EXC-120 series microscopes are highly regarded by the veterinary community for their dependable operation and crisp images.  Each of these microscopes is on display at the Avante Animal Health booth this week at VMX 2023.  The 3000-LED is outfitted with an Excelis HD LITE camera with attachable HD monitor.  The Excelis HD LITE features built-in software for stand-alone operation without a PC.  The SKY WiFi 2 WiFi-enabled camera is shown on the EXC-120 microscope.  Simply download the SKYE View 2 mobile app to an Android or Apple mobile device, scan the QR code on the top of the SKYE WiFi camera and the specimen images are displayed right on your mobile device.  You can also capture and share images directly from your mobile device.  For more information or to see a demonstration, please visit Avante Animal Health in booth 1308.

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As a market leader in quality microscopy and imaging solutions, ACCU-SCOPE blends precision, performance and outstanding value like no other manufacturer can. We deliver superb yet affordable optical instrumentation and microscopy innovations that help advance the work, improve the outcomes and empower the achievements of the demanding professionals we’re privileged to serve.

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Understanding Depth of Field and Depth of Focus in Microscopes

Depth of field and depth of focus are both well-known terms in photography, filmography, and microscopy. Given how similar their names are, they have sometimes been used interchangeably. However, despite both playing a vital role in camera and microscope optics, the two are very much different. Let’s look more closely at what defines the depth of field and depth of focus, their role in microscopy, and why the two should not be confused with one another.

Depth of Field

The depth of field is the distance between the closest object plane in focus and the furthest one in focus. In other words, it can be considered a lens’s ability to retain the quality of an image without moving the object farther or closer to the frame. Depth of field relates to how much detail can be seen above and below the optimal focus position.  When objects are placed at a set focal distance away from a lens, detail can blur and thereby degrade the resolution. As a result, smaller objects naturally lead to reduced depth of field for the lens. It is worth noting that the depth of field will increase as the condenser numerical aperture (condenser aperture diaphragm) is closed down (approaches zero).  While depth of field increases when the condenser aperture closes, resolution decreases.

Depth of Focus

Depth of focus is the imaging complement to depth of field and is more concerned with the tilt of the sensor plane of the microscope with respect to the lens image plane. This concept relates to how the quality of focus is altered as the object stays still and the lens’s sensor side changes. Therefore, the depth of focus will change significantly based on the magnification of the object and the microscope’s ability to focus light, known as the numerical aperture. Depth of focus has little to do with sensor size and is more closely related to sensor perpendicularity to the optical axis and pixel count — the more pixels the sensors have, the more noticeable sensor tilt will be on the quality of the image. Given how digital camera sensors are exposed at a given focal plane, depth of focus impacts the quality of the resulting image and is an essential consideration in photomicrography.

Depth of Focus vs. Depth of Field: How They Differ

As described above, depth of field and depth of focus relate to different perspectives. However, they are not entirely separate, as they both correspond to the axial depth of the space of a particular plane — depth of field relates to object space, whereas the depth of focus involves image space. This, in turn, influences their applications. For example, low-power objective lenses generally have lower numerical apertures and will have a higher depth of field (detail is lost quickly above or below the optimal focus plane) and higher depth of focus (sensor tilt is less impactful to image quality), while high-power objective lenses will have almost the reverse.

For Microscopes and More, Give Us a Call

Now that you have a better understanding of the depth of focus vs. depth of field differences and how they affect the quality of microscopes, see their influences for yourself with the help of ACCU-SCOPE’s high-quality microscope products. We offer a range of upright, inverted and dissection microscopes and various microscope accessories for laboratory settings and other environments. To learn more information about our products, give us a call today.

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ACCU-SCOPE Introduces ioLight Portable Digital Microscopes

Commack, NY – ACCU-SCOPE Inc. is please to introduce the line of ioLight portable digital microscopes to its portfolio.  Developed by ioLight Limited (UK), ioLight microscopes are designed for maximum portability and functionality in field work, the classroom and the laboratory.  The agreement with ioLight makes ACCU-SCOPE a master distributor of ioLight microscopes in North America, Latin America and the Caribbean, extending distribution through ACCU-SCOPE’s extensive dealer network.

ioLight microscopes are currently available in 1mm and 2mm field of view (FOV) models, without or with a microscope slide XY stage to aide in slide positioning.  Equipped with top and bottom illumination, the user focuses on the specimen simply by sliding the camera head down the mast.  Fine focusing, illumination intensity and camera control are conducted from within the ioLight app on a smartphone or via a browser on any computer (Windows, MacOS or Chromebooks).  Snap an image or record a quick video and share it instantly via email or SMS.  The microscopes fold flat for storage and maximum transportability.

The size, convenience and performance of ioLight portable microscopes make them ideal for field studies where decisions can be made on the spot, eliminating the need to send samples to a lab and thereby saving scientists both time and money.  One very popular application is monitoring the nation’s waterways, lakes and oceans for harmful algal blooms (HABs).  HABs impact every state in the US and can cost the US economy tens of millions of dollars each year.  Field-based monitoring puts experts on location with the equipment they need to make rapid decisions and share their findings with colleagues and peers.  Read about NOAA’s $18.9M grant program for HAB research and monitoring: https://www.noaa.gov/news-release/noaa-awards-189m-for-harmful-algal-bloom-research-monitoring

Coming soon are improved and enhanced ioLight products including an updated inverted microscope (for observing samples in flasks or Petri dishes, such as cells in culture in incubators), and models of the 1mm, 2mm and inverted equipped for fluorescence microscopy and imaging. “CONTACT US for more information about ioLight portable digital microscopes.”